In that case, this medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as acetaminophen, ibuprofen) may also be prescribed. Ask your doctor or pharmacist about using hydromorphone safely with other drugs. It is not known whether this medicine will harm an unborn baby. If you use hydromorphone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born.
Dilaudid Solution – Uses, Side Effects, and More
If the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed by the product’s prescribing information. DILAUDID INJECTION may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of DILAUDID INJECTION and know how they will react to the medication. Proper addiction and recovery assessment of the patient, proper prescribing practices, periodic reevaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs. DILAUDID INJECTION (hydromorphone hydrochloride) is supplied in clear and colorless single-dose prefilled syringes. Each single-dose prefilled syringe of sterile, aqueous solution contains 0.2 mg, 0.5 mg, 1 mg or 2 mg hydromorphone hydrochloride with 0.2% sodium citrate and 0.2% citric acid solution.
Patient Access to Naloxone for the Emergency Treatment of Opioid Overdose
Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away hydromorphone to any other person is against the law. Consider prescribing naloxone if the patient has household members (including children) or other close contacts at risk for accidental ingestion or overdose. Strongly advise patients and caregivers to always use a graduated oral syringe or measuring cup, with metric units of measurements (i.e., mL), to correctly measure the prescribed amount of medication.
1 Important Dosage and Administration Instructions
Teach your family or household members about the signs of an opioid overdose and how to treat it. Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, sweating, flushing, or dry mouth may occur. Some of these side effects may decrease after you have been using this medication for a while. Hydromorphone is known in various countries around alcohol and seizures can alcohol or withdrawal trigger a seizure the world by the brand names Hydal, Dimorphone, Exalgo, Sophidone LP, Dilaudid, Hydrostat, Hydromorfan, Hydromorphan, Hymorphan, Laudicon, Opidol, Palladone, Hydromorph Contin, and others. Medicines that interact with Dilaudid may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Dilaudid.
11 Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness
Do not use Dilaudid if you have used a MAO inhibitor in the past 14 days. Inform patients and caregivers that oral dosing devices may be obtained from their pharmacy and to never use household teaspoons or tablespoons to measure DILAUDID Oral Solution. Instruct patients and caregivers on how to accurately measure and take or administer the correct dose of DILAUDID Oral Solution. Titan’s last visit to that veterinarian was in January 2022 for an illness check, during which there was no visible mass, but the doctor warned Titan might have one because he had nasal discharge, signs of a narrowing airway and irregular heart rate. Alvarez was sent home with a seven-day supply of medication to treat a heart condition and nasal mass and was told to re-check with his regular veterinarian as soon as possible. However, Alvarez failed to follow up with veterinary care after Titan’s visit.
Missed Dose
These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Low levels of opioid analgesics have been detected in human milk. Neonatal opioid withdrawal syndrome presents as irritability, hyperactivity and abnormal sleep pattern, high pitched cry, tremor, vomiting, diarrhea, and failure to gain weight. The onset, duration, and severity of neonatal opioid withdrawal syndrome vary based on the specific opioid used, duration of use, timing and amount of last maternal use, and rate of elimination of the drug by the newborn. Observe newborns for symptoms of neonatal opioid withdrawal syndrome and manage accordingly [see WARNINGS AND PRECAUTIONS].
- The terminal elimination half-life of hydromorphone after an intravenous dose is about 2.3 hours.
- Naloxone hydrochloride nasal spray is currently available both over-the-counter and by prescription, under different brand names.
- They’ll ultimately prescribe the smallest dosage that provides the desired effect.
- It may be possible for some users to experience none at all.
The extended-release tablet is used for people who need daily, around-the-clock pain treatment. The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with opioid agonists. The pharmacokinetics of hydromorphone are affected by renal impairment. Start patients with renal impairment on one-fourth to one-half the usual starting dose depending on the degree of impairment. Patients with renal impairment should be closely monitored during dose titration [see CLINICAL PHARMACOLOGY]. Hydromorphone is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function.
Talk with your doctor about other drug options that may work for you. This may cause lightheadedness, dizziness, and even fainting. Your doctor may start you on a lowered dosage or a different schedule. This can help keep levels of this drug from building up too much in your body.
DILAUDID INJECTION contains hydromorphone, a substance with high potential for misuse and abuse, which can lead to the development of substance use disorder, including addiction [see WARNINGS AND PRECAUTIONS]. Access to drugs with a potential for abuse such as DILAUDID INJECTION presents an occupational hazard for addiction in the health care industry. Routine procedures for handling controlled substances developed to protect the public may not be adequate to protect health care workers. DILAUDID INJECTION is indicated for the management of pain severe enough to require an opioid analgesic and for which alternate treatments are inadequate. However, one study demonstrates that Dilaudid is used more often now for medical and surgical pain.
Opioids are sought for nonmedical use and are subject to diversion from legitimate prescribed use. Consider these risks when prescribing or dispensing DILAUDID INJECTION. Strategies to reduce these risks include prescribing the drug in the smallest appropriate https://sober-home.org/alcohol-and-anxiety-causes-risks-and-treatment/ quantity. Contact local state professional licensing board or state-controlled substances authority for information on how to prevent and detect abuse or diversion of this product. DILAUDID INJECTION contains hydromorphone, a Schedule II controlled substance.
Because of similar pharmacological properties, it is reasonable to expect similar risk with the concomitant use of other CNS depressant drugs with opioid analgesics [see DRUG INTERACTIONS]. While serious, life-threatening, or fatal respiratory depression can occur at any time during the use of DILAUDID INJECTION, the risk is greatest during the initiation of therapy or following a dosage increase. DILAUDID INJECTION should not be used for an extended period of time unless the pain remains severe enough to require an opioid analgesic and for which alternative treatment options continue to be inadequate. Dilaudid and morphine are opioid medications for short-term treatment of moderate to severe pain. If you have ongoing pain (such as due to cancer), your doctor may direct you to also take long-acting opioid medications.
Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Hydromorphone oral liquid and tablets are used to relieve pain. When a narcotic medicine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly.